Pain-Related and Electrically Stimulated Somatosensory Evoked Potentials in Patients with Machado-Joseph Disease and Multiple System Atrophy.

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  • YAMAMOTO Masahiko
    The Department of Neurology, Chubu National Hospital The Department of Neurology, Nagoya University School of Medicine
  • KACHI Teruhiko
    The Department of Neurology, Chubu National Hospital
  • SOBUE Gen
    The Department of Neurology, Nagoya University School of Medicine

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  • Pain-Related and Electrically Stimulate

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We investigated the ascending somatosensory pathway for pain in 8 patients with Machado-Joseph disease (MJD) and multiple system atrophy (MSA). Pain-related somatosensory evoked potentials (pain SEPs) by CO2 laser stimulation were examined together with conventional electrically stimulated somatosensory evoked potentials (electric SEPs). The sporadic cerebellar ataxia of patients with MSA showed a normal pattern of pain SEPs as well as electric SEPs. However, pain and electric SEPs were abnormal for the central and/or peripheral ascending pathway in MJD. These abnormalities of pain and electric SEPs in MJD were not related to the clinical severity of sensory impairment, but they indicate that MJD presents a subclinical abnormality for the ascending somatosensory pathways not only for vibratory sense but also for pain sense.<br>(Internal Medicine 36: 550-555, 1997)

収録刊行物

  • Internal Medicine

    Internal Medicine 36 (8), 550-555, 1997

    一般社団法人 日本内科学会

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