Hemolytic Uremic Syndrome-associated Encephalopathy Successfully Treated with Corticosteroids

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  • Hosaka Takashi
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Nakamagoe Kiyotaka
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Tamaoka Akira
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan

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説明

<p>The encephalopathy that occurs in association with hemolytic uremic syndrome (HUS), which is caused by enterohemorrhagic Escherichia coli (E. coli), has a high mortality rate and patients sometimes present sequelae. We herein describe the case of a 20-year-old woman who developed encephalopathy during the convalescent stage of HUS caused by E.coli O26. Hyperintense lesions were detected in the pons, basal ganglia, and cortex on diffusion-weighted brain MRI. From the onset of HUS encephalopathy, we treated the patient with methylprednisolone (mPSL) pulse therapy alone. Her condition improved, and she did not present sequelae. Our study shows that corticosteroids appear to be effective for the treatment of some patients with HUS encephalopathy. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 56 (21), 2937-2941, 2017

    一般社団法人 日本内科学会

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