Multi-organ Involvement of Sweet's Syndrome: A Case Report and Literature Review

  • Li Bo
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China Department of Occupational Disease Prevention, Jilin Provincial Occupational Disease Prevention and Treatment, China
  • Ma Zhongsen
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Xu Xuesong
    Chinese Japanese Union Hospital, Jilin University, China
  • Yin Jinzhi
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Wang Xiuli
    Department of Hematology and Oncology, The Second Clinical Hospital, Jilin University, China
  • Ren Jin
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Wang Songyan
    Department of Nephrology, Jilin Provincial People's Hospital, China
  • Yang Junling
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Ma Tiangang
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Zhang Qinghua
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Yu Jinyan
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China
  • Yan Bingdi
    Department of Respiratory Medicine, The Second Clinical Hospital, Jilin University, China

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Abstract

The hallmark of Sweet's syndrome (SS) is the infiltration of mature neutrophils in the upper dermis. We herein report a case of SS with multi-organ involvement. A 32-year-old man presented with fever, anemia and dyspnea. He was given antibiotics, without any improvements. Later, a number of erythematous lesions appeared, accompanied by deteriorating respiratory and cardiovascular functions. A diagnosis of SS was confirmed on a skin biopsy, and the patient was given corticosteroids, the dose of which was reduced after one month. The organ function subsequently deteriorated, and he ultimately died of multi-organ failure. Early recognition of SS with multi-organ involvement is important in patients with SS.<br>

Journal

  • Internal Medicine

    Internal Medicine 54 (3), 339-343, 2015

    The Japanese Society of Internal Medicine

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