Recurrent Kikuchi-Fujimoto Disease Successfully Treated by the Concomitant Use of Hydroxychloroquine and Corticosteroids
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- Honda Fumika
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Tsuboi Hiroto
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Toko Hirofumi
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Ohyama Ayako
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Takahashi Hidenori
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Abe Saori
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Yokosawa Masahiro
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Asashima Hiromitsu
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Hagiwara Shinya
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Hirota Tomoya
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Kondo Yuya
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Matsumoto Isao
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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- Sumida Takayuki
- Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan
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説明
<p>Kikuchi-Fujimoto disease (KFD) is a benign disease of unknown etiology characterized by lymphadenopathy and a fever. For the majority of patients with KFD, the course is self-limited; however, the optimum method of managing recurrent cases has not yet been established. We herein report a case of a 42-year-old Japanese woman with KFD (confirmed by a lymph node biopsy). Although high-dose prednisolone (PSL) rapidly induced remission, she experienced four recurrences on treatment tapering. Concomitant use of hydroxychloroquine (HCQ) with low-dose PSL induced continuous remission. This is the first case to suggest the effectiveness of HCQ for recurrent KFD in a Japanese patient. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 56 (24), 3373-3377, 2017
一般社団法人 日本内科学会
