On the proliferation regulatory mechanism of spontaneously transformed L cell (L-N)

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  • MATSUI Hideki
    First Department of Physiology, Okayama University Medical School

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  • 自然形質転換したL細胞(L-N)の増殖制御機構について
  • シゼン ケイシツ テンカンシタ L サイボウ L N ノ ゾウショク セイギョ

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Abstract

1) The L-O cell absolutely required serum for proliferation, but L-N cell grew rapidly in serum free medium.<br>2) L-N cell cultured in MEM medium with TPB reached high saturation density as in serum containing medium.<br>3) The growth rate of L-N cell in serum free medium was dependent on initial density of cell population just before logarithmic growing phase.<br>4) L-N cell rounded cell cycle from G-1 phase to S phase 4 hours faster than L-O cell.

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