Genome-wide Association Study for Eating Disorders : Current Progress and Future Directions(Panel Discussion/Molecular Mechanisms of Obesity and Eating Disorders)

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  • Nakabayashi Kazuhiko
    Department of Cell Biology, Faculty of Medicine, Fukuoka University:Department of Maternal-Fetal Biology, National Center for Child Health and Development
  • Shirasawa Senji
    Department of Cell Biology, Faculty of Medicine, Fukuoka University

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  • ゲノムワイド解析による摂食障害遺伝子の探索と今後の課題(パネルディスカッション : 肥満・摂食障害の分子機構,2006年,第47回日本心身医学会総会(東京))
  • ゲノムワイド解析による摂食障害遺伝子の探索と今後の課題
  • ゲノムワイド カイセキ ニ ヨル セッショク ショウガイ イデンシ ノ タンサク ト コンゴ ノ カダイ

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We performed a genomewide case-control association study using 23465 highly polymorphic microsattellite(MS) markers that are selected to cover the entire human genome, and identified eleven markers associated with anorexia nervosa (AN). We have completed SNP-based association study to further define a disease susceptibility region on four prioritized loci that contain genes with brain/neuron-related functions, and successfully identified gene(s) or haplotype block (s) associated with AN.

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