Discovery of Novel Hypothalamic Neuropeptides Related to Stress
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- Ueta Yoichi
- Department of Physiology, School of Medicine, University of Occupational and Environmental Health, Japan
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- Sakamoto Fumihiko
- Department of Occupational Health, Matsushita Science Center of Industrial Hygiene
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- Yamada Seiji
- Department of Occupational Health, Matsushita Science Center of Industrial Hygiene
Bibliographic Information
- Other Title
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- ストレスに関連する視床下部の新しい神経ペプチド遺伝子の発見
- ストレス ニ カンレン スル シショウカブ ノ アタラシイ シンケイ ペプチド イデンシ ノ ハッケン
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Abstract
G-protein coupled receptors (GPCRs) for unknown endogenous ligands are called as orphan receptors. Recently novel biologically active substances including peptides have been discovered as unknown ligands of orphan GPCRs. Some of them are neuropeptides that are expressed in the hypothalamic areas that are known to be important sites to integrate the autonomic, neuroendocrine and immune responses to the stress. In this review we focused on novel neuropeptides that are orexins, neuromedin U and galanin-like peptide as candidates of mediators of the stress responses via the hypothalamus.
Journal
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- Japanese Journal of Psychosomatic Medicine
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Japanese Journal of Psychosomatic Medicine 45 (5), 323-330, 2005
Japanese Society of Psychosomatic Medicine
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Details 詳細情報について
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- CRID
- 1390001204890852096
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- NII Article ID
- 110001523473
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- NII Book ID
- AN00121636
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- ISSN
- 21895996
- 03850307
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- NDL BIB ID
- 7335771
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed