Dietary Factors and Dietary Patterns and Depressive Symptoms(Symposium/Nutritional Psychiatry and Behavioral Medicine : New Possibilities for Prevention and Treatment for Depression and Anxiety)

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  • Nanri Akiko
    Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine
  • Mizoue Tetsuya

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Other Title
  • 食事・栄養要因および食事パターンと抑うつ症状との関連(シンポジウム:精神栄養・行動医学 : 抑うつや不安の予防・治療における新しい可能性,2013年,第54回日本心身医学会総会ならびに学術講演会(横浜))
  • 食事・栄養要因および食事パターンと抑うつ症状との関連
  • ショクジ ・ エイヨウ ヨウイン オヨビ ショクジ パターン ト ヨクウツ ショウジョウ ト ノ カンレン

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We examined the association of serum folate, vitamin B_6, and vitamin D and dietary patterns with depressive symptoms among Japanese workers and observed the following results. 1) Higher folate concentrations at baseline were associated with lower prevalence of depressive symptoms after 3 years in men. 2) The prevalence of depressive symptoms after 3 years tended to decrease with increasing vitamin B_6 concentrations at baseline. 3) The prevalence of depressive symptoms tended to decrease with increasing vitamin D concentrations in late autumn. 4) A healthy Japanese dietary pattern characterized by high intakes of vegetables, fruit, soy products, and mushrooms was associated with decreased prevalence of depressive symptoms. A healthy Japanese dietary pattern was associated with higher intakes of folate, vitamin C, and vitamin E, which have shown to be associated with decreased depression. The inverse association with the dietary pattern may be ascribed to the combined effect of these nutrients on mood. The present study has some limitations including small sample size. Further study is required to examine the association in large-scale, prospective, and intervention study.

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