Determination of Antioxidative Sites of Capsaicin
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- OKADA Youji
- Department of Analytical Chemistry
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- SHUTO Aki
- Department of Analytical Chemistry
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- OKAJIMA Haruo
- Department of Analytical Chemistry
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- YOSHIZAWA Kiyoyoshi
- Department of Nursing and School Health Care, Faculty of Health Sciences, Kyorin University
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- OSAWA Akiko
- Department of Nursing and School Health Care, Faculty of Health Sciences, Kyorin University
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- KUREBAYASHI Yusuke
- Department of Nursing and School Health Care, Faculty of Health Sciences, Kyorin University
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- OTAKI Junichi
- Department of Nursing and School Health Care, Faculty of Health Sciences, Kyorin University
Bibliographic Information
- Other Title
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- カプサイシンの抗酸化活性部位の特定に関する研究
- Two Different Approaches by Kinetics and Molecular Orbital Method
- 速度論および分子軌道計算からのアプローチ
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Abstract
We investigated the antioxidative sites of capsaicinhave the phenol moiety of CAP but has a acetamide (CAP) by discussing the structuring-activity of CAP and moiety, did not show the antioxidant activity. These using molecular orbital theory. First, the guaiacol results indicate that the phenolic hydrogen of CAP is the derivatives showed the effective antioxidant activity on site of antioxidant activity and its activity of CAP is the oxidation of cumene. Furthermore, CAP and these independent on the benzyl hydrogen and acetamide guaiacol derivatives have almost the same antioxidant moiety. In addition, these suggestions were confirmed activity in these experimental conditions. However, N -by calculating the electrostatic potential energy of CAP benzylacetamide, a related compound which does not using the molecular orbital energy method.
Journal
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- JOURNAL OF THE KYORIN MEDICAL SOCIETY
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JOURNAL OF THE KYORIN MEDICAL SOCIETY 43 (4), 107-114, 2013
The Kyorin Medical Society
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Details 詳細情報について
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- CRID
- 1390001204893240832
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- NII Article ID
- 130003364529
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- ISSN
- 1349886X
- 03685829
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed