Effects of Volatile Anesthetics, Isoflurane and Sevoflurane, on Peripheral Circulation : Study Using the Impedance Cuff Method

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  • OHASHI Tsutomu
    Department of Anesthesiology, Kyorin University School of Medicine

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  • イソフルラン,セボフルランの末梢循環に対する影響について : インピーダンス・カフ法による研究

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The impedance cuff method is a newly developed technique for evaluating the peripheral circulation, giving the peripheral blood flow (BF) and volume elastic modulus (Ev) which indicates the elastance of peripheral arteries. Twenty-three patients undergoing gynecologic surgery were anesthetized with isoflurane (Group I, n=12) or sevoflurane (Group S, n=11), and the impedance cuff method was applied to the left index finger. Arterial blood pressure and pulse rate were then monitored. The volatile anesthetics at 1.3 minimum alveolar concentration (MAC) or 0.4 MAC were serially administered with 66 % nitrous oxide and the remainder oxygen for 30min, respectively, and the data were collected every 5 min. There was no significant intra- or inter-group difference in the arterial blood pressure. Pulse rate was significantly higher (p<0.05) in Group I than in Group S. BF was significantly lower in Group I than in Group S at 1.3 MAC. The value of Ev decreased after induction of anesthesia in both groups, and remained low in Group I, whereas it increased in Group S at 0.4 MAC. Ev in Group I was significantly lower than that in Group S at 0.4 MAC (p<0.05). These data suggest that Ev measured by the impedance cuff method is a sensitive parameter for monitoring the peripheral circulation.

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