Histochemical and Electron Microscopic Studies on Biopsied Muscle from a Patient with Myotonic Dystrophy
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- KOIKE Hidemi
- Department of Internal Medicine, Kyorin University School of Medicine
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- YOSHINO Yoshikazu
- Department of Internal Medicine, Kyorin University School of Medicine
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- KOYAMA Shigeki
- Department of Pathology, Kyorin University School of Medicine
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- AKAI Keiichiro
- Department of Pathology, Kyorin University School of Medicine
Bibliographic Information
- Other Title
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- 筋緊張性ジストロフィー症の一例 : 生検筋の組織化学的および電顕的検討
- 筋緊張性ジストロフィー症の1例--生検筋の組織化学的および電顕的検討
- キン キンチョウセイ ジストロフィーショウ ノ 1レイ セイケン キン ノ ソ
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Abstract
Microscopic and electron microscopic studies were performed on muscle obtained at biopsy from a 35-year-old man with myotonic dystrophy. Microscopically, in addition to the selective type-1 atrophy which have been emphasized in the literature, changes were observed in type-II fiber, namely the increase in the fiber diameter and the reduction of the fiber population, as well as the destruction of the fiber structure. An electron microscopic examination revealed various diffuse changes in the subcellular structures, such as the fragmentation and the derangement of myofibrils, the swelling and the gathering of mitochodria, and the proliferation of sarcoplasmic reticulum. A lattice-like network of tubules was observed and the correlation of this abnormal structure with myotonic phenomenon was discussed.
Journal
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- JOURNAL OF THE KYORIN MEDICAL SOCIETY
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JOURNAL OF THE KYORIN MEDICAL SOCIETY 7 (2), 77-83, 1976
The Kyorin Medical Society
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Details 詳細情報について
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- CRID
- 1390001204898229504
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- NII Article ID
- 110002698116
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- NII Book ID
- AN00062945
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- ISSN
- 1349886X
- 03685829
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- NDL BIB ID
- 1714624
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed