Long-Term Feeding Test of Sanpoly-305 in Rats.

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  • ラットにおけるSanpoly-305の長期経餌投与試験

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Sanpoly-305 was mixed in feed at 3 different concentrations-100ppm, 1000ppm, and 2500ppm-and fed to rats for 79 weeks. Animals did not show any symptoms up to 52-week except for occasional decrement of general state by murine pneumonia. From 53-week on, they showed so called senile changes as discharge of viscous eye mucus, hypokinesia and etc., but there were no specific symptoms related to the agent administration. No specific effect related to the agent administration was not seen in incidence and types of the tumors occurred in the present study.

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