糖尿病性網膜症を有する患者の予後  心,脳,下肢の大血管合併症の影響

書誌事項

タイトル別名
  • Life Prognosis in Diabetic Patients with Retinopathy-Influence of macrovascular complications in heart, brain, and lower extremities.
  • トウニョウビョウセイ モウマクショウ オ ユウスル カンジャ ノ ヨゴ : ココロ,ノウ,カシ ノ ダイ ケッカン ガッペイショウ ノ エイキョウ
  • Influence of macrovascular complications in heart, brain and lower extremities
  • 心, 脳, 下肢の大血管合併症の影響

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抄録

To investigate the influence of macroangiopathy (MA) on the prognosis of diabetic subjects with retinopathy, we studied the prevalence of ischemic heart disease (IHD), cerebral infarction (CI), and arteriosclerosis obliterans (ASO) in 827 type 2 diabetic patients. Stages of retinopathy were defined as none (group N, n=495), simple (group S, n=216), and proliferative (group P, n=116). Complicated MA (MA score) was used as a marker of systemic atherosclerosis. Prevalence of IHD, CI, and ASO increased significantly with progressive retinopathy and the MA score was the highest in group P. Mortality rate (/1000 person·year) of subjects in groups N, S, and P during the 4-year observation period was 5.6, 24.3, and 66.8. Cardiovascular and/or sudden death tended to be associated with proliferative retinopathy. Multivariate analysis suggests life prognois was influenced independently by nephropathy, autonomic neuropathy, and MA score (especially ASO and IHD). Glycemic control, other atherogenic risk factor management, and noninvasive evaluation systemic MA are thus important in improving the prognosis in diabetic with proliferative retinopathy.

収録刊行物

  • 糖尿病

    糖尿病 44 (1), 23-29, 2001

    一般社団法人 日本糖尿病学会

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