Measurement of Exercise Endurance in Type 2 Diabetic Patients Using a Bicycle Ergometer. Possible Relationship between Anaerobic Threshold(AT) and Intima-media Thickness(IMT) of Common Carotid Artery.

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  • 糖尿病患者におけるエルゴメーターを用いた運動能力の測定　　特に頚動脈内膜中膜複合体肥厚度（ＩＭＴ）との関連
  • トウニョウビョウ カンジャ ニ オケル エルゴメーター オ モチイタ ウンドウ ノウリョク ノ ソクテイ : トクニ ケイドウミャク ナイマク チュウマク フクゴウタイ ヒコウド(IMT)ト ノ カンレン
  • Possible Relationship between Anaerobic Threshold (AT) and Intima-media Thickness (IMT) of Common Carotid Artery
  • 特に頸動脈内膜中膜複合体肥厚度 (IMT) との関連

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We studied exercise endurance (anaerobic threshold; AT) in type 2 diabetic patients in relation to atherosclerotic change measured as intima-media thickness (IMT) of the carotid artery and other parameters such as the coexsistence of hypertension (HT), body mass index (BMI), glycemic control, fasting serum insulin, and C-peptide (sCPR) concentration. A strong negative correlation was observed between AT and HT, BMI, and s-CPR through multiple regression analysis. IMT was correlated with HT, HbA1c or s-CPR except for age. In patients with AT exceeding 4 Mets (n=54), IMT was significantly (p<0.05) lower than in other patients with AT less than 4 Mets (n=48). This data suggests that a lack of exercise is related to atherosclerosis, probably through the existence of hypertension, obesity, and/or insulin resistance.

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