- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Automatic Translation feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
An NIDDM Patient with Repeated Postprandial Hypotension Successfully Treated with Amezinium Methylsulfate.
-
- Kanda Tsutomu
- Division of Gastroenterology and Metabolism, Department of Internal Medicine, Osaka Prefectural General Hospital
-
- Imano Eiichi
- Division of Gastroenterology and Metabolism, Department of Internal Medicine, Osaka Prefectural General Hospital
-
- Matsushima Hiroyuki
- Division of Gastroenterology and Metabolism, Department of Internal Medicine, Osaka Prefectural General Hospital
-
- Wada Masahiko
- Division of Gastroenterology and Metabolism, Department of Internal Medicine, Osaka Prefectural General Hospital
-
- Hayaishi Rieko
- Division of Gastroenterology and Metabolism, Department of Internal Medicine, Osaka Prefectural General Hospital
-
- Kimura Takashi
- Division of Nurology, Department of Internal Medicine, Osaka Prefectural General Hospital
Bibliographic Information
- Other Title
-
- 反復する食事性低血圧にメチル硫酸アメジニウムが奏効したNIDDMの1例
Search this article
Description
We encountered an NIDDM patients with the complication of postprandial hypotension (PPH) who repeatedly experienced syncope after meals. The patient was successfully treated with amezenium methylsulfate which increased endogenous norepinephrine levels and blood pressure.<BR>The patient, a 66-year-old woman, was diagnosed with NIDDM in 1971 and treated with oral hypoglycemic agents. Thereafter, she maintained poor glycemic control. Since she repeatedly experienced post prandial syncope with palpitation which lasted up to ten minutes and occurred once or twice amonth beginning in February 1993, she was hospitalized in August 1993. We noted that she had a history of syncope after meals, and performed 24-hour ambulatory blood pressure monitoring (AMBP) and 2-hour AMBP during a 75g oral glucose tolerance test (OGTT). She was diagnosed with NIDDM complicated by PPH based on complaints of general fatigue as well as a systemic blood pressure (SBP) decrease of 25mmHg. The concentrations of plasma norepinephrine (NE) were 338pg/ml before OGTT and 268pg/ml after OGTT. When she was given 10mg of amezinium methylsulfate (AM) per os 2hours before OGTT, the decrease in SBP was only 12 mmHg. The patient had no further complaints and plasma NE concentrations increased from 290 pg/ml before OGTT to 348pg/ml after OGTT.<BR>These results indicate that PPH in this case was caused by the intake of meals including glucose. PPH improved rapidly with AM administration which increased plasma NE.
Journal
-
- Journal of the Japan Diabetes Society
-
Journal of the Japan Diabetes Society 39 (2), 153-159, 1996
THE JAPAN DIABETES SOCIETY
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390001204905735168
-
- NII Article ID
- 130004338263
- 10005564435
-
- NII Book ID
- AN00166576
-
- ISSN
- 1881588X
- 0021437X
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- CiNii Articles
-
- Abstract License Flag
- Disallowed