Five Cases with Spontaneous Hypoglycemia Probably Caused by Impaired Renal Gluconeogenesis

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  • “腎性低血糖”とも称せられるべき自発性低血糖症の5症例
  • 症例報告 "腎性低血糖"とも称せられるべき自発性低血糖症の5症例
  • ショウレイ ホウコク ジンセイ テイケットウ トモ ショウセラレル ベキ ジハツセイ テイケットウショウ ノ 5 ショウレイ

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We report 5 cases with spontaneous hypoglycemia (BS≤50 mg/dl) after 2 to 3-day fasting who were on hemodialysis due to end-stage renal disease. Except for 1 case having 7 U insulin glargine injection 38 hrs prior to a hypoglycemic episode, none had taken any hypoglycemic agents for at least a few days. No case showed abnormally high insulin or low counter regulatory hormone in blood determined in the early morning at latest the 4th day after the episode. Impaired renal gluconeogenesis is most likely a major cause of hypoglycemic episodes except for 1 case with alcohol-induced liver dysfunction.

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