Two Cases of Postherpetic Neuralgia Recurring after Withdrawal of Kampo Medicine Including Uzu

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  • NOGAMI Tatsuya
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • OKA Hiroshi
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • FUJIMOTO Makoto
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • HIKIAMI Hiroaki
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • GOTO Hirozo
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • SHIBAHARA Naotoshi
    Department of Kampo Diagnostics, Institute of Natural Medicine, University of Toyama
  • SHIMADA Yutaka
    Department of Japanese Oriental Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

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Other Title
  • 烏頭剤の中止により再発した帯状疱疹後神経痛の２例
  • ウズザイ ノ チュウシ ニ ヨリ サイハツ シタ タイジョウホウシンゴ シンケイツウ ノ 2レイ

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We experienced two cases of postherpetic neuralgia (PHN) improved with Kampo medicines that include uzu (i.e. uzu-zai).<br>The pain from PHN was improved via the administration of an uzu-zai in these 2 cases, worsened by its discontinuation, and improved again by its re-introduction.<br>Case 1 : A 76-year-old male suffering from PHN of the right L 2-3 area was administered uzukeishito and obtained pain reduction. After 12 months, his prescription was changed from uzukeishito to keishikaryoju-tsubuto. Then, after only 2 days his pain worsened again. Uzukeishito treatment was re-instated, and he again obtained pain reduction. Case 2 : An 82-year-old male suffering from PHN of the right C 4-5 area was given uzuto and obtained pain relief. After 3 months his prescription was changed from uzuto to keishikajutsubuto. Then, after only1week his pain worsened again. Uzuto was then re-introduced, and pain reduction was achieved again. These two cases led to two suggestions. First, that the uzu-zais were very effective against the PHN pain. Second, that this effect of an uzu-zai against PHN pain might be a symptomatic rather than a radical treatment.<br>These two cases highlight the fact that the use of an uzu-zai was instrumental in reducing PHN-associated pain, but further studies will be needed to determine a dosage protocol, including when and at what pace uzu-zais might be reduced/discontinued.

Journal

  • Kampo Medicine

    Kampo Medicine 62 (3), 369-373, 2011

    The Japan Society for Oriental Medicine

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