Three Cases of Falsely Elevated Levels of Serum SCC Antigen Due to Formation of High Molecular Weight SCC Antigen
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- Shima Yukio
- Department of Clinical Chemistry, Toranomon Hospital
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- Tsukada Toshihiko
- Department of Clinical Chemistry, Toranomon Hospital
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- Nakamori Yoshitaka
- Department of Respiratory Disease, Toranomon Hospital
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- Shimizu Taeko
- Department of Endocrinology and Metabolism, Toranomon Hospital
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- Nakayama Toshimasa
- Department of Clinical Chemistry, Toranomon Hospital
Bibliographic Information
- Other Title
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- 血清SCC抗原高値の原因が高分子量SCC抗原であった3症例
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Description
We determined levels of squamous cell carcinoma (SCC) antigen in sera obtained from three patients with sustained high levels but without evidence of carcinoma. High-performance liquid chromatography (HPLC) revealed two to three SCC antigen peaks, one of which eluted at the authentic molecular weight, and the others at a larger one. The sera were not adsorbed by antibodies to IgG, IgA or IgM, and were not inactivated by heating at 56° for 30 min. We demonstrated that the rise in serum SCC antigen in patients without carcinoma could be attributed to the larger molecular weight forms.
Journal
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- Japanese Journal of Clinical Chemistry
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Japanese Journal of Clinical Chemistry 21 (2), 131-137, 1992
Japan Society of Clinical Chemistry
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Details 詳細情報について
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- CRID
- 1390001204911221248
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- NII Article ID
- 130003357979
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- ISSN
- 21874077
- 03705633
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed
