Usefulness of the Thioglycerol as an Activator of CK (creatine kinase) in a Stable Liquid-Type Reagent

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  • 活性化剤としてチオグリセロールを用いたCK(クレアチンキナーゼ)活性測定試薬の有用性

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We found thioglycerol to be stable activator for CK, and can replace NAC as a CK assay reagent. Thioglycerol was more stable than NAC, and did not produce oxidizing substances which inhibit CK activity. Thus, it is preferable to formulate a stable reagent with a longer shelf life. CK values in human serum samples tested with the thioglycerol-activated reagent agreed with the JSCC consensus method (automated method). The thioglycerol-activated CK assay was suitable for a stable liquid-type reagent.

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