A Case of Signet-ring Cell Carcinoma of the Extrahepatic Bile Duct with Bile Duct Resection

DOI Web Site 8 References
  • Okazaki Taro
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Ajiki Tetsuo
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Shinozaki Kenta
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Murakami Sae
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Yoshida Yuko
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Matsumoto Ippei
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Fukumoto Takumi
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine
  • Kawakami Fumi
    Department of Diagnostic Pathology, Kobe University Hospital
  • Hara Shigeo
    Department of Diagnostic Pathology, Kobe University Hospital
  • Ku Yonson
    Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine

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Other Title
  • 肝外胆管原発印環細胞癌に対して胆管切除術を施行した1例

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We report a case of signet-ring cell carcinoma of the extrahepatic bile duct. A 76-year-old woman with abdominal pain was referred to a clinic because of acute cholangitis. She underwent percutaneous transhepatic gallbladder drainage with administration of antibiotics. MRCP demonstrated a bile duct stricture from the upper to middle bile duct. Abdominal CT revealed an irregular mass with enhanced effect in the same region as shown by MRCP. Histological examination of the biopsy specimens from a stenotic portion revealed possible tubular adenocarcinoma. She underwent bile duct resection for curative operation under a diagnosis of carcinoma of the middle bile duct. The histological diagnosis was signet-ring cell carcinoma of the bile duct. The patient is alive without any evidence of recurrence 24 months after surgery.

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