Mixed Mesodermal Tumor of the Female Genital Tract

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  • INOUE Masaki
    Department of Obstetrics and Gynecology, Osaka University
  • VEDA Galko
    Department of Obstetrics and Gynecology, Osaka University
  • SATO Yasuko
    Department of Obstetrics and Gynecology, Osaka University
  • YAMASAKI Masato
    Department of Obstetrics and Gynecology, Osaka University
  • HIRAMATSU Keizo
    Department of Obstetrics and Gynecology, Osaka University
  • KURACHI Keichi
    Department of Obstetrics and Gynecology, Osaka University
  • IDE Tatsuo
    Department of Obstetrics and Gynecology, Kaizuka City Hospital

Bibliographic Information

Other Title
  • 子宮及び膣の中胚葉性混合腫瘍
  • シキュウ オヨビ チツ ノ チュウ ハイヨウセイ コンゴウ シュヨウ ジケン
  • —Report of Four Cases with a Brief Review of the Literature—
  • ―自験4症例の報告と文献的考察―

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Abstract

Mixed mesodermal tumor of the female genital tract is a relatively rare and highly malignant disease. In Japanese literature, 67 cases have thus far been reported. In this paper, we added 4 such cases as follows, and discussed the definition, histogenesis, classification and treatment of this disease.<br>Case 1. A 54-year old female, gravida 4, para 2, was hospitalized because of a giant pelvic mass which protruded from the fundus uteri and adhered with the transverse colon, descendence colon and sigmoid colon. Supravaginal hysterectomy and left-adnexectomy were performed and followed by chemotherapy. Microscopically, the tumor was composed predominantly of spindle cell sarcoma and admixed rarely with the cartilage.<br>Case 2. A 56-year old female, gravida 2, para 2, was hospitalized because of a grape-like tumor which ocuppied the uterine cavity. Radical hysterectomy with pelvic lymphadenectomy was performed and followed by chemotherapy. Microscopically, spindle cell sarcoma and adenocarcinoma were equivalently identified.<br>Case 3. A 71-year old female, gravida 6, para 6, was hospitalized because of a cauliflower-like tumor which arose from the posterior fornix of the vagina. She was treated by irradiation therapy. Microscopically, both adenocarcinoma and sarcoma elements were admixed and the cartilage was also identified.<br>Case 4. A 49-year old female, gravida 2, para 2, was hospitalized because of an adult head-sized cervical tumor with the metastases to the lung, vagina and external urethral orfice. Simple total hysterectomy, both side adnexectomy and the resection of the tumors at the vagina and external urethral orfice, were performed. Microscopically, undifierentiated adenocarcinoma and spindle cell sarcoma were equivalently identified

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