原発性卵巣黒色腫の1例

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  • Primary Melanogenic Ovarian Tumor-Report of A Case-
  • ゲンパツセイ ランソウ コクショクシュ ノ 1レイ

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The melanogenic ovarian tumor, particularly as a primary lesion, is extremely rare. In the world literature, only 15 cases have been reported since Andrews' case (1901), but none in Japan.<br>We experienced the first case with the primary melanogenic ovarian tumor in Japan, which was studied cytologically, histologically and electron microscopically.<br>The case: A 48 year-old Japanese woman, gravida 9, para 3-0-6-3, who complained of lower abdominal distension and pain, and hypermenorrhea, was laparotomized under the diagnosis of the uterine myoma and the left ovarian tumor. In the abdominal cavity, the left man's fist sized, smooth-surfaced black ovarian mass filled with serous black fluids and the uterine rnyoma and 100ml of black ascites were seen. The peritoneal surface including the large net was black-stained like spots and patches. The careful cytological, histological and electron microscopic examinations were performed. Intracellular black pigments were confirmed melanin granules by positive Fontana' s reaction, bleaching reaction and Lillie's reaction. But in spite of careful examinations, these melanin containing cells were not melanocytes, but macrophages, and only mucinous cystadenoma was found.<br>It was concluded that, though melanocytes were not confirmed in the ovarian mass, this tumor was considered as the primary melanogenic ovarian tumor originating from the ovarian teratoid tumor, probably benign

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