Cholinergic Fibers and Muscarinic Receptors in the Central Auditory System

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  • Hamada Satoko
    Department of Otolaryngology, Kansai Medical University Department of Anatomy and Brain Science, Kansai Medical University
  • Trifonov Stefan
    Department of Anatomy and Brain Science, Kansai Medical University
  • Houtani Takeshi
    Department of Anatomy and Brain Science, Kansai Medical University
  • Kase Masahiko
    Department of Anatomy and Brain Science, Kansai Medical University
  • Yamashita Yuji
    Department of Anatomy and Brain Science, Kansai Medical University
  • Baba Kazuyasu
    Department of Otolaryngology, Kansai Medical University
  • Shimizu Jun-ichi
    Department of Otolaryngology, Kansai Medical University Department of Anatomy and Brain Science, Kansai Medical University
  • Maruyama Masato
    Department of Anatomy and Brain Science, Kansai Medical University
  • Tomoda Koichi
    Department of Otolaryngology, Kansai Medical University
  • Yamashita Toshio
    Department of Otolaryngology, Kansai Medical University
  • Sugimoto Tetsuo
    Department of Anatomy and Brain Science, Kansai Medical University

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Other Title
  • 中枢聴覚系のコリン線維とムスカリン性受容体

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Abstract

It was reported that central auditory dysfunction was evident in subjects with even mild cases of Alzheimer's disease. Major auditory stations in diseased brain manifested marked degenerative changes. This communication briefly summarized our morphological data on the distribution of cholinergic fibers and receptors in the ascending auditory stations of mouse brain. We revealed considerable involvements of m2 and m3 muscarinic receptors in several auditory stations, providing some morphological support for the cholinergic projections and receptors available to the auditory system.<br>

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