脳損傷に対する認知リハビリテーションとしての，Ｐ３００　Ｂｉｏｆｅｅｄｂａｃｋ　Ｔｈｅｒａｐｙの提唱

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  • Proposal of P300 Biofeedback Therapy in Patients with Mental Disturbance as Cognitive Rehabilitation.
  • ノウ ソンショウ ニ タイスル ニンチ リハビリテーション トシテノ P300

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説明

P300 is one of event-related potential which is closely related with cognitive function. P300, occurring when a subject attends a target stimulus intermingled with more frequently presented nontarget stimuli, has been used to diagnose a mental disturbance like dementia. In this study, we designed P300 Biofeedback Therapy (P3BF), using auditory oddball paradigm as cognitive rehabilitation. Patient, who sat 1m in front of an evoked potential machine, had to watch a P300 waveform on a screen of evoked potential machine. If there was a poorly developed P300 waveform, he was explained before and during training that it indicated that his attention was not enough and he should pay more attention to the tones. Five patients (2cases in head injury, 1 case in cerebral hemorrhage, 1 case in temporal lobectomy, 1 ease in bacterial encephalitis) who showed chronic mental disturbance received a four-week period of P3BF at least after 4 months of disease onset in addition to a full-time inpatient rehabilitation program. P3BF lasted 30 minutes 3 times per week. They gave a helpful co-operation to this training.<br>These five patients showed remarkable improvement of WAIS and WMS, compared with a comparison period of 4 weeks of a full-time inpatient rehabilitation program without P3BF.<br>These findings indicated that P3BF is a useful cognitive rehabilitation, and furthermore, it can be called one of remediation of attentional deficit from the characteristics of P300.

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