Higher Brain Dysfunction in Patients with Pulmonary Rehabilitation in the Chronic Obstructive Pulmonary Disease.

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  • WATANABE Mihoko
    Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine
  • MEGURO Kenichi
    Section of Neuropsychology Division of Disability Science, Tohoku University Graduate School of Medicine
  • GOTO Yoko
    Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine
  • SATO Tokutaro
    National Institute of Rehabilitation Center for the Disabled
  • KOHZUKI Masahiro
    Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine

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Other Title
  • 呼吸リハビリテーションを施行した慢性閉塞性肺疾患患者における高次脳機能障害の検討　　その頻度と特徴について
  • コキュウ リハビリテーション オ シコウ シタ マンセイ ヘイソクセイ ハイ シッカン カンジャ ニ オケル コウジ ノウ キノウ ショウガイ ノ ケントウ ソノ ヒンド ト トクチョウ ニ ツイテ
  • その頻度と特徴について

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Abstract

We assessed the frequency and the characteristics of higher brain dysfunction in COPD patients undergoing pulmonary rehabilitation and controls. The COPD patients showed significant decrease in neuropsychological examination scores especially in verbal memory compared with control patients. The decline of verbal memory paralleled that of other cognitive functions. Significant positive correlation was found between cognitive function and PO2 is the severe COPD group. The finding of Brain Magnetic Resonance Imaging has not been associated with neuropsychological examination scores. These results indicate that higher brain dysfunction is seen in most of the COPD patients, and suggest the need for devising an appropriate way of instructing pulmonary rehabilitation program in these patients.

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