Detection of circulating Wuchereria bancrofti antigen, filaria specific IgG and IgG4 in chyluria cases in Japan.
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- ITOH MAKOTO
- Department of Parasitology, Aichi Medical University
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- QIU XU-GUANG
- Department of Parasitology, Aichi Medical University
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- KOYAMA YUZO
- Department of Urology, University of the Ryukyus School of Medicine
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- OGAWA YOSHIHIDE
- Department of Urology, University of the Ryukyus School of Medicine
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- WEERASOORIYA MIRANI V.
- Department of Papasitology, Faculty of Medicine, University of Ruhuna
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- VISANOU HANESANA
- Department of Parasitology, Aichi Medical University
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- FUJIMAKI YASUNORI
- Department of Parasitology, Institute of Tropical Medicine, Nagasaki University
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- KIMURA EISAKU
- Department of Parasitology, Aichi Medical University
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Abstract
Serum samples from Japanese chyluria patients were examined for filaria specific antibodies and a circulating filarial antigen in order to know if the symptom was filarial in origin. All the sera were negative for the circulating antigen. Anti-Brugia pahangi antibodies were detected in 6 out of 16 serum samples by ELISA after absorption of the sera with Anisakis and Dirofilaria immitis antigens. One of the positive sera showed a high titer for anti-B. pahangi IgG4, suggesting that Wuchereria bancrofti adults were surviving in the patient in recent years. Detection of antibodies would be helpful for immunodiagnosis of filarial chyluria in Japan, where filarial origin is often determined based simply on the history of residence in the past endemic areas.
Journal
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- Japanese Journal of Tropical Medicine and Hygiene
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Japanese Journal of Tropical Medicine and Hygiene 27 (4), 483-486, 1999
Japanese Society of Tropical Medicine
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Details 詳細情報について
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- CRID
- 1390001204952270208
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- NII Article ID
- 10011519367
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- NII Book ID
- AN00196023
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- ISSN
- 21861781
- 21861811
- 03042146
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- HANDLE
- 10069/22433
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- NDL BIB ID
- 4947359
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed