Studies on effects of paromonycin sulphate, bithionol, mebendazole and flubendazole in the treatment of mice infected with plerocercoids of Diphyllobothrium erinacei.

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  • MAKI JUN
    Department of Parasitology, Kitasato University School of Medicine
  • YANAGISAWA TOSHIO
    Department of Parasitology, Kitasato University School of Medicine

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Other Title
  • マンソン孤虫に対する硫酸パロモマイシン, ビチオノール, メベンダゾールおよびフルベンダゾールの駆虫効果に関する実験的研究
  • マンソン孤虫に対する硫酸パロモマイシン,ビチオノール,メベンダゾールおよびフルベンダゾールの駆虫効果に関する実験的研究〔英文〕
  • マンソン コチュウ ニ タイスル リュウサン パロモマイシン ビチオノール メ

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Abstract

Mice infected with Diphyllobothrium erinacei plerocercoids were administered orally with paromomycin sulphate, bithionol, mebendazole and flubendazole at the total doses of 10, 000 mg/kg for 200 days or subcutaneously with the drugs at the total doses of 2, 500 mg/kg for 25 days. In spite of the high doses, no difference was observed between the number and weight of larvae recovered from mice in experimental groups and those in control groups.

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