フィラリア感染好適宿主としてのMongolian gerbilの基礎的検討

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  • Basic studies on the Mongolian gerbil as a susceptible host to filarial infection; Comparative studies on hematological features between the wild-colored gerbil and the coat color mutants.
  • COMPARATIVE STUDIES ON HEMATOLOGICAL FEATURES BETWEEN THE WILD-COLORED GERBIL AND THE COAT COLOR MUTANTS

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Hematological baseline parameters of the Mongolian gerbils were investigated to be compared between the wild-colored gerbil (agouti type) and the other coat color mutants such as white spotted-agouti, albino, black and white spotted-black type. Erythrocyte counts of the agouti type were higher than those of the coat color mutants. But, there was no significant difference. A frequent occurrence of polychromasia and basophilic stippling in circulating erythrocytes was known to be a particular feature of the Mongolian gerbil among laboratory animals. The polychromasia and the basophilic stippling were proved to be present in the coat color mutants in the same degree as the agouti type. As to sex dimorphism in erythrocytic values, it was only hemoglobin concentration that was observed significant sex-related difference in all coat color gerbils. In leukocytic values, quantitative sex-related difference was not seen in this experiment. A presence of basophils in peripheral blood was observed on all blood films of all coat color gerbils. These results confirmed that the coat color mutants of gerbils had the same unique hematological characteristics as an agouti type.

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