シリコン製サック一体型三葉弁の試作と補助人工心臓への応用

書誌事項

タイトル別名
  • Silicone Tri-leaflet Valve and Silicone Blood Chamber made en bloc for Ventricular Assit Device.

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説明

A blood chamber with a silicone lenticular sac and two silicone tri-leaflet valves made en bloc was manufactured using die caster for a ventricular assist device (VAD) that would be less expensive. Regurgitation of the silicone valve was measured 205ml/min, and that of Björk-Shiley monostrut valve was measured 321ml/min. Pressure gradient across the silicone valve was slightly greater than that across the monostrut valves. By this VAD, the maximam output flow of 6.3L/min was achieved at the rate of 80bpm in a Donovan type mock circulatory system, which was selected the preload of 12mmHg, the afterload of 120mmHg, the driving pressure of 160mmHg, the driving vacuum of 20mmHg and the percent systole 35%. The VAD worked well for 54 days in an overflow type mock circulatory system at the afterload of 100mmHg.

収録刊行物

  • 人工臓器

    人工臓器 26 (3), 645-649, 1997

    一般社団法人 日本人工臓器学会

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