実験結核症に対する4,4'-diisoamyloxy-thiocarbanilide(lsoxyl)の抗結核作用について

豊原 希一, 重松 昭世, 稲垣 博一, 初鹿野 浩, 大里 敏雄

doi:10.11400/kekkaku1923.41.73

実験結核症に対する4,4'-diisoamyloxy-thiocarbanilide(lsoxyl)の抗結核作用について

DOI Web Site

豊原希一

結核予防会結核研究所
重松昭世

結核予防会結核研究所
稲垣博一

結核予防会結核研究所
初鹿野浩

結核予防会結核研究所
大里敏雄

結核予防会結核研究所

書誌事項

タイトル別名

ANTITUBERCULOUS ACTIVITY OF 4, 4'-DIISOAMYLOXY-THIOCARBANILIDE (ISOXYL) AGAINST EXPERIMENTAL TUBERCULOSIS
ジッケンケッカクショウニタイスル 4 , 4 -diisoamyloxy-thiocarbanilide Isoxyl ノコウケッカクサヨウニツイテ

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説明

Many experimental studies were already made on antituberculous activity of Isoxyl, and most of them say that it is generally effective for experimental tuberculosis except one reporting its ineffectiveness for tuberculosis of guinea pigs.<BR>Isoxyl bound with stearic acid (Isoxyl-stearate) was synthesized recently, and so the authors tried to investigate the effect of Isoxyl against tuberculosis of mice, and then the antituberculous activity against tuberculosis of guinea pigs was compared among Isoxyl, Isoxylstearate and 1314 TH.