弗化第一錫の齲蝕予防効果に関する研究

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タイトル別名
  • STUDIES ON THE PREVENTION OF DENTAL CARIES WITH STANNOUS FLUORIDE
  • フッカ ダイイチ スズ ノ クショクヨボウ コウカ ニ カンスル ケンキュウ 4
  • IV. THE UPTAKE OF FLUORINE AND TIN IN OR ON PROTECTED ENAMEL POWDER
  • IV. 弗化第一錫処理エナメル質粉末にUptakeされた弗素量, 錫量について

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In the recent reseach of topical application of fluoride, Muhler and his coworkers reported that stannous fluoride is more effective than sodium fluoride. In this experiment, the amounts of fluorine or tin in or on protected powdered enamel were determined, which was treated with 2per cent solution of sodium fluoride or 1, 2, 4, 8 or 16 per cent solution of stannous fluoride respectively. The procedure was as follows. Using mechanical shaker, 100mg. of 100-150 mesh enamel powder was treated with sodium fluoride or stannous fluoride solution for 5 minutes at 20°C. respectively, (single application) and in addition, the samples similarly treated four times in repetition were also prepared. For determing fluorine in enamel powder, samples were ashed and steam-distilled, and determined with Zirconium-Alizarin method. Samples protected similarly prepared served also for determination of tin. They were dissolved in 4 N HCl and determined with Cacotherine method. Following conclusions were obtained.<BR>1. Samples treated four times with 2%NaF contained about triple amounts of fluorine as compared with that of singly applied samples.<BR>2. In case of SnF2 application, singly treated samples contained 50-60 μg of fluorine per 100mg, while four times treated one contained fluorine only 10-20 μg over that in single applications mentioned above.<BR>3. The uptake of tin in samples treated with 1% or 2% SnF2 were much more than that treated with 8 % or 16 % SnF2. Such tendency was more marked in case of four times applications.<BR>Considering the uptake of fluorine or tin in enamel together with acid solubility of powdered enamel treated with SnF2, the amounts of uptake of tin appeared to play a dominant role in reducing the acid solubility of enamel, particularly in the earlier decalcifying stage.

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