Effect of 3.8% Ag(NH_3)_2F Solution as an Anti-caries Agent on Dentin in Artificial Mouth Model System using Actinomyces naeslundii

DOI Web Site 1 Citations 26 References
  • USUI Yoshie
    Division of Gerontology and Gerodontology, Department of Gerodontology, Graduate School, Tokyo Medical and Dental University:Department of Oral Health, National Institute of Public Health
  • IMAI Susumu
    Department of Oral Health, National Institute of Public Health
  • SAITO Noriko
    National Institute of Infectious Disease
  • HANADA Nobuhiro
    Department of Oral Health, National Institute of Public Health
  • UEMATSU Hiroshi
    Division of Gerontology and Gerodontology, Department of Gerodontology, Graduate School, Tokyo Medical and Dental University

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Other Title
  • Actinomyces naeslundiiを用いた人工口腔装置における3.8%フッ化ジアミン銀の象牙質う蝕抑制効果
  • Effect of 3 8パーセント Ag NH3 2F Solution as an Anti caries Agent on Dentin in Artificial Mouth Model System using Actinomyces naeslundii

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Abstract

The object of this study was to evaluate the effect of 3.8% and 38% Ag (NH_3)_2F solutions as a caries-preventive agent on dentin surfaces in the artificial mouth model system. A total of 36 bovine dentin slabs were divided into three groups : 3.8% Ag (NH_3)_2F and 38% Ag (NH_3)_2F application groups and a control group. Actinomyces naeslundii, selected as having an important role in dentin caries, was used in this experiment. Several parameters concerning caries development were evaluated by the following methods : the amount of artificial biofilm, the changes in pH, the changes in dentin microhardness measured by a hardness tester, and element quantitative analysis for silver and fluorine elements by an energy dispersive X-ray micro analyzer. The dentin specimens in the 3.8% and 38% Ag (NH_3)_2F application groups had significantly less hardness reduction than the specimens in the control group (p<0.05). Little difference, however, was observed for the dentin hardness reduction between the two test solution groups. The amounts of silver and fluorine elements on the specimen surface between the two groups were not significantly different after a lapse of 60 hours. The outcomes in this study suggest that 3.8% Ag (NH_3)_2F solution might have similar effectiveness as 38% Ag (NH_3)_2F solution as a preventive agent for dentin caries.

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