Fluticasone Propionate Aqueous Nasal Spray for the Treatment of Chronic Sinusitis with Eosinophil
-
- Ohta Yasushi
- Otorhinolaryngology of Omiya Medical Center Jichi Medical School
-
- Tsubaki Keiju
- Otorhinolaryngology of Omiya Medical Center Jichi Medical School
-
- Yamamoto Masanori
- Otorhinolaryngology of Omiya Medical Center Jichi Medical School
-
- 児玉 梢
- 自治医科大学付属大宮医療センター耳鼻咽喉科
-
- Makino Nobuko
- Department of Otorhinolaryngology, Jichi Medical School
-
- Ishikawa Toshio
- Department of Otorhinolaryngology, Jichi Medical School
-
- Ichimura Keiichi
- Department of Otorhinolaryngology, Jichi Medical School
Bibliographic Information
- Other Title
-
- 好酸球性副鼻腔炎に対するフルチカゾン噴霧療法(倍量投与)の試み
- コウサンキュウセイ フクビクウエン ニ タイスル フルチカゾン フンム リョウホウ バイリョウ トウヨ ノ ココロミ
Search this article
Description
Chronic sinusitis with eosinophils easily recurs after endoscopic sinus surgery. The condition is usually complicated by asthma, and many eosinophils are present in the sinus mucosa. One conservative treatment method is the administration of glucocorticoids locally or systematically. To evaluate the efficacy and tolerability of intranasal fluticasone propionate for the treatment of chronic sinusitis with eosinophils, seven patients with chronic sinusitis with eosinophils were treated over a 12-week period using a fluticasone propionate aqueous nasal spray (800μg per day in each nostrilz). The Symptons of 7 patients, especially nasal discharge and nasal obstructions, improved and an expanded air space was observed on paranasal CT images. The percent of drug systemically available after intranasal administration varied by less than 1% for intranasal fluticasone propionate. Therefore, even if intranasal fluticasone propionate is administerved at double the usual dose, it is unlikely to cause systemic side effects. Fluticasone propionate aqueous nasal spray at double the usual dose is effective for the treatment of chronic sinusitis with eosinophils.
Journal
-
- Nippon Jibiinkoka Gakkai Kaiho
-
Nippon Jibiinkoka Gakkai Kaiho 109 (3), 157-162, 2006
Japanese Society of Otorhinolaryngology-Head and neck surgery
- Tweet
Details 詳細情報について
-
- CRID
- 1390001205004965632
-
- NII Article ID
- 10019255375
- 10019726894
-
- NII Book ID
- AN00191551
-
- COI
- 1:STN:280:DC%2BD283gvVyrtA%3D%3D
-
- ISSN
- 18830854
- 00306622
- http://id.crossref.org/issn/00306622
-
- NDL BIB ID
- 7900506
-
- PubMed
- 16615430
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
-
- Abstract License Flag
- Disallowed