頸部感染巣より発症した劇症型A群溶連菌感染症の1例

書誌事項

タイトル別名
  • A Case of Toxic Shock-like Syndrome Affecting the Neck
  • ケイブ カンセン ソウ ヨリ ハッショウ シタ ゲキショウガタ Aグン ヨウレンキン カンセンショウ ノ 1レイ

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説明

Toxic shock-like syndrome (TSLS) is a form of rapidly progressing septic shock that can lead to multiple organ failure and has a high mortality rate of 30%. We report a rare case of TSLS affecting the head and neck. A 40-year-old man complained of redness and swelling of the neck with vomiting and diarrhea. His blood pressure dropped, and multiple organ failure occurred.<br>Streptcoccus pyogenes, Group A, was identified in a blood culture, and he was diagnosed as having TSLS. He was treated with high-dose carbapenem, clindamysin, and gamma globulin. Continuous hemodiafiltration (CHDF) and PMX-DHP was applied to prevent sepsis and multiple organ failure. Debridement of the neck was performed on day 16. He recovered gradually and was discharged from hospital on day 45. A total resection is required to treat TSLS, but such a procedure is difficult to perform in the head and neck region. Our case improved without resection but after debridement and general control.<br>TSLS should be first treated by medication and then by surgery, consisting of either debridement or resection.

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