音響負荷前後の蝸牛反応の変動についての慢性実験的研究

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  • 菊田 晃
    福島県立医科大学耳鼻咽喉科学教室

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  • EXPERIMENTAL STUDIES ON COCHLEAR MICROPHONIC CHANGE TO REPETITIONS OF INTENSE SOUND
  • 音響負荷前後の蝸牛反応の変動についての慢性実験的研究(大内仁教授開講20周年記念論文)
  • オンキョウ フカ ゼンゴ ノ カタツムリ ハンノウ ノ ヘンドウ ニ ツイテ

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Twenty normal adult rabbits with implanted electordes on the round window were used as experimental animals.<br>These animals were divided into three groups in which they were exposed to 90, 100 and 100dB(SPL)of pure tones at 2kHz for two hours a day respectively.Coclear microphonics (CM)were measured immediately and twenty-two hours after each exposure.<br>According to this experiment, five patterns of the daily change of CM were recognized;unaffected type, recovery type, recovery type, injury type and injury type.<br>In most of cases, it was found that CM reduction immediately after exposure and CM recovery twenty-two hours after exposure became gradually unremarkable following the consecutive days of the experiment, and CM amplitude after twenty-two hours of recovery time after tone stimulation gradually increased day by day.This phenomenon was observed on 1 kHz, 2kHz and 4kHz test tones and in addition to this fact, the rate of CM reduction immediately after expoure was remarkable in order of 1 kHz, 2kHz and 4kHz.<br>This phenomenon seemed to relate to habituation of the middle ear muscles because the experiment was done without anaesthesia and the rate of CM reduction immediately after exposure to low frequency test tone was remarkable.

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