THERAPEUTIC EFFICACY OF ZINC PICOLINATE IN PATIENTS WITH TASTE DISORDERS

  • SAKAI FUMITAKA
    Department of Otorhinolaryngology, Nihon University School of Medicine
  • YOSHIDA SHINYA
    Department of Otorhinolaryngology, Nihon University School of Medicine
  • ENDO SOHEI
    Department of Otorhinolaryngology, Nihon University School of Medicine
  • TOMITA HIROSHI
    Department of Otorhinolaryngology, Nihon University School of Medicine

Bibliographic Information

Other Title
  • 味覚障害に対するピコリン酸亜鉛の効果
  • 二重盲検法による有効性の検討

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Description

We studied the therapeutic efficacy of zinc picolinate in patients with zinc-deficient and idiopathic taste disorders. Efficacy was assessed in a double-blind study. The following findings were obtained:<BR>1. There was a significant difference between the zinc picolinate and placebo groups in the grade of improvement shown by the filter-paper disk method.<BR>2. There was a significant difference between the zinc picolinate and placebo groups in the serum zinc concentration.<BR>3. There was no significant difference between the two groups in the degree of total subjective recovery or the grade of improvement, as shown by in the whole mouth method.<BR>4. We conclude that the administration of zinc picolinate is effective for patients with zincdeficient and idiopathic taste disorders.

Journal

  • Nippon Jibiinkoka Gakkai Kaiho

    Nippon Jibiinkoka Gakkai Kaiho 98 (7), 1135-1139,1255, 1995

    Japanese Society of Otorhinolaryngology-Head and neck surgery

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