Clinical Study of Malignant Lymphomas of the Nasal Cavity and Paranasal Sinuses

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  • 鼻副鼻腔原発悪性リンパ腫の検討―下鼻甲介腫大を呈する症例の紹介―
  • ハナ フクビコウ ゲンパツ アクセイ リンパシュ ノ ケントウ : シタ ビ コウカイシュダイ オ テイスル ショウレイ ノ ショウカイ
  • ―Introduction of Inferior Turbinate Swelling Type Cases―

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Abstract

<p> The difficulty in the diagnosis of malignant lymphoma is often attributed to various local and imaging findings. We reviewed 36 cases of malignant lymphomas of the nasal cavity or paranasal sinuses diagnosed at our hospital between 2006 and 2016. A detailed review of the local, imaging, and biopsy findings from patient charts and images was conducted.</p><p></p><p> Regarding the local findings, abnormalities were easily identified in patients with necrosis, mass formation, and bleeding, but not in patients with inferior turbinate swelling without mucosal change. Overall, we observed 5, 18, 9, and 8 cases of necrosis, mass formation, bleeding, and inferior turbinate swelling, respectively. Regarding the computed tomography findings, only two cases had a permeative spread, in which the tumor spread across the thin bone wall. Malignant lymphoma was diagnosed in all cases based on biopsy findings. One-time biopsy was the most common, although in a rare case, three biopsies were required before making the diagnosis.</p><p></p><p> Conclusion: In patients with malignant lymphoma of the nasal cavity and paranasal sinuses, plural cases were observed to have inferior turbinate swelling without mucosal change. In these instances, it was difficult to recognize the abnormal findings. Hence, histopathological examination is advisable in cases of turbinate swelling to rule out malignant lymphoma.</p>

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