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- 粉川 信行
- 慶応義塾大学医学部耳鼻咽喉科学教室
書誌事項
- タイトル別名
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- A New Surgical Procedure for Dysphonias Due to Androgenic and Anabolic Hormones
- ホルモン オンセイ ショウガイ ニ タイスル アタラシイ チリョウホウ
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Androgenic and anabolic hcrmones have often been used in treating various diseases. The treatment for dysphonia, one of their side effects, has not yet been ascertained. We have employed a new surgical procedure and have obtained successful results.<BR>It may be said that when the cricothyroid muscle is more dominant than the thyroarytenoid (TA) muscle, voice will be high-pitched.<BR>Based on this concept, a method of weakening the activity of the TA muscle was assumed to be effective for eliminating abncrmal high-pitched voice. Prior to clinical application, we designed electrophysiological and histochemical experiments.<BR>Using canine larynx, a portion of the terminal branch of the recurrent nerve in the TA muscle was severed by making an incision onto the vocal cord parallel to its free edge. By deepening the incision, evoked electromyographic activity was gradually decreased presumably due to reduction in action potentials of the muscle fibers to be picked up by the electrodes. Similar results were also obtained in chronic experiments using canine larynx.<BR>A histochemical study revealed that motor end-plates were remarkably degenerated one month after ncision. This finding would indicate that the incision has severed the branch in the TA muscle.<BR>This method have been successfully employed for 8 clinical cases. In this paper, the results were reported and descussed from the viewpoint of phoniatric examinations.
収録刊行物
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- 日本気管食道科学会会報
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日本気管食道科学会会報 28 (6), 323-332, 1977
特定非営利活動法人 日本気管食道科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205014641536
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- NII論文ID
- 130003668588
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- NII書誌ID
- AN00187474
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- ISSN
- 18806848
- 00290645
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- NDL書誌ID
- 1919563
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- NDL
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