Ethylene Oxideによる気管狭窄の実験的研究 (予報)

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タイトル別名
  • Experimental Study on Tracheal Stenosis Following Ethylene Oxide Gas Sterilization-Pa
  • Ethylene Oxide ニヨル キカン キョウサク ノ ジッケンテキ ケ
  • Pathological Finding
  • 主として病理組織学的観察から

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The authors previously reported two clinical cases of tracheal stenosis in children following intratracheal intubation and suggested a possibility of chemical effect of residual ethylene oxideused for sterilization of the tube on the tracheal mucosa.<BR>In the present study, animal experiments were performed on 7 dogs in order to investigate the effect of residual ethylene oxide on the laryngotracheal mucosa. The result suggested that there was a positive relationship between the aeration time after sterilization and the degree of histological changes in the mucosa.<BR>Based on the result of the present study, it was suggested that aeration time should be longer in order to avoid possible damage to the airway mucosa.

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