Sinobronchial syndrome and it's related subjects. Therapy of sinobronchial syndrome-low-dose long-term chemotherapy of erythromycin in diffuse panbronchiolitis.

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Other Title
  • 副鼻腔気管支症候群とその周辺　　治療　　とくにびまん性汎細気管支炎に対するエリスロマイシン小量長期投与

Abstract

Diffuse panbronchiolitis (DPB) which is the representative of Japanese sinobronchial syndrome is grave in prognosis. Eighteen paients with DPB, including sixteen cases with H. influenzae infection and two with P. aeruginosa infection, were treated with 600mg of Erythromycin (EM) per day for 19.8 months on an average. After the therapy, dyspnea on exertion, body weight, chest X-ray findings, pulmonary function data including VC, FEV1.0 and RV/TLC, PaO2, cold agglutinin titer and IgM level were significantly improved. There were no significant side effects. There was no change of bacterial flora in sputum except one.<br>Low-dose, long-term chemotherapy of EM could be useful in treatment of DPB.

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Details 詳細情報について

  • CRID
    1390001205015573888
  • NII Article ID
    130003669118
  • DOI
    10.2468/jbes.38.193
  • ISSN
    18806848
    00290645
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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