Hypopharyngeal Carcinoma and Intestinal Leiomyosarcoma Associated with von Recklinghausen's Disease. A Case Report.

DOI 18 References
  • Koshii Kenji
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Hirabayashi Keishi
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Shono Noboru
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Fujisawa Tsutomu
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Ohgaki Haruyuki
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Uno Kohei
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Hirabayashi Hideki
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Hinohara Tadashi
    Department of Bronchoesophagology, Dokkyo University School of Medicine
  • Monma Kimitsune
    Second Department of Surgery, Dokkyo University School of Medicine

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Other Title
  • 下咽頭癌と小腸平滑筋肉腫を合併したｖｏｎ　Ｒｅｃｋｌｉｎｇｈａｕｓｅｎ病の１例

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Abstract

We encountered a case having cutaneous neurofibromatosis associated with intestinal leiomyosarcoma and hypopharyngeal carcinoma. The patient was a 57-year-old female, who was hospitalized at Dokkyo University Hospital in September 1993 complaining of dysphagia. Various tests were made, and a tumor was found at the posterior wall of the right piriformis sinus. As a result of a punch biopsy from the hypopharynx, the patient was diagnosed as having “well-differentiated squamous cell carcinoma. ”By radiotherapy of the hypopharynx, her general condition was temporarily improved, but she underwent an operation for a recurrence of the dysphagia on May 30, 1994. Histopathologically, a three-tumor duplication was found after the operation. This consisted of cutaneous neurofibromatosis, leiomyosarcoma of the small intestine and well-differentiated squamous cell carcinoma of the hypopharynx. Tumor duplication is often seen in neurofibromatosis. Careful observation of patients with von Recklinghausen's disease is necessary.

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