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- 平山 雅清
- 東京大学医科学研究所病態薬理学研究部 東京都立駒込病院内科
書誌事項
- タイトル別名
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- Analysis of data concerning humoral immunity in cases of sinobronchial syndrome.
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抄録
Sinobronchial syndrome (S. B. S.) is a clinical entity which exhibits a combination of chronic paranasal sinusitis in the upper respiratory tract and chronic pulmonary inflammation in the lower respiratory tract. There is approximately 70-80% of diffuse panbronchiolitis (D. P. B.) cases are complicated by chronic paranasal sinusitis, therefore DPB might be a part of SBS. It has been reported that the prevalence of HLA-Bw54 is correlated well with SBS disease, including DPB.<br>In 31 DPB patients, 39 SBS patients not included in the DPB category and 30 non-SBS patients with chronic lung disease. laboratory data including γ-gloculin, complement, rheumatoid factors, cold hemagglutinin (CHA) and HLA system were measured and analyzed statistically. IgG titers above the normal range were found in both the above patient groups. IgA, latex agglutination test and CHA titers were significantly higher in the first group containing DPB patients than in the other 2 groups. In the first group, IgG, IgA, latex agglutination test and CHA titers did not differ between the Bw54 positive cases and the negative cases. In the second group, containing SBS patients not included in the DPB category, titers of IgG, IgA, latex agglutination test, and CHA also did not differ between the Bw54 positive and negative cases. However, application of Hayashi's second method of quantification to all SBS patients produced results indicating that correlations between IgG and Bw54, IgA and DPB, latex agglutination test and DPB, CHA and DPB were all significant.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 24 (2), 109-115, 1986
社団法人 日本呼吸器学会