Successful use of Fluconazole Against Semi-invasive. Pulmonary Aspergillosis.

  • Mizuguchi Masayuki
    The Division of Pulmonary Medicine, Ishikawa Prefectural Central Hospital
  • Nishi Kouich
    The Division of Pulmonary Medicine, Ishikawa Prefectural Central Hospital
  • Amemiya Tokunao
    The Division of Pulmonary Medicine, Ishikawa Prefectural Central Hospital
  • Tachibana Hideki
    The Division of Pulmonary Medicine, Ishikawa Prefectural Central Hospital
  • Ohka Takio
    The Division of Pulmonary Medicine, Ishikawa Prefectural Central Hospital
  • Kurumaya Hiroshi
    The Division of Pathology, Ishikawa Prefectural Central Hospital
  • Fujimura Masaki
    Department of Internal Medicine, Kanazawa University, School of Medicine
  • Matsuda Tamotsu
    Department of Internal Medicine, Kanazawa University, School of Medicine

Bibliographic Information

Other Title
  • フルコナゾールが奏効した肺アスペルギルス症“semi‐invasive type”の1例
  • invasive -Pulmonary Aspergillosis

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Abstract

A 53-year-old man was admitted to the hospital because of productive coughing general malaise, and right-sided chest pain. At 41 years of age he was given a diagnosis of gastric cancer, underwent a and gastrectomy, was treated with anti-cancer drugs.<br>At 49 years of age he suffered from atypical mycobacteriosis and received anti-tuberculosis drugs for 1 year. A chest X-ray film showed infiltrative shadows with a cavity in the right upper lung field. Semi-invasive aspergillosis was diagnosed on the basis of the clinical and radiographic findings, positive sputum cultures, and positive serologic tests. After 8 months of therapy with intravenous and oral fluconazole, no pulmonary aspergillosis was evident. Tretment with fluconazole was effective in this case of semi-invasive aspergillosis.

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