Mediastinal Lymph Node Metastasis of Follicular Thyroid Carcinoma with Extensive Chest Wall Invasion

DOI Web Site Web Site 4 References
  • Kono Michihisa
    Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University
  • Nomura Kenichiro
    Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University
  • Kitada Masahiro
    Department of Respiratory Surgery, Asahikawa Medical University
  • Katada Akihiro
    Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University
  • Hayashi Tatsuya
    Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University
  • Harabuchi Yasuaki
    Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University

Bibliographic Information

Other Title
  • 広範囲胸壁浸潤をきたした甲状腺濾胞癌縦隔リンパ節転移
  • 症例 広範囲胸壁浸潤をきたした甲状腺濾胞癌縦隔リンパ節転移
  • ショウレイ コウハンイ キョウヘキ シンジュン オ キタシタ コウジョウセン ロホウガン ジュウカク リンパセツ テンイ

Search this article

Abstract

<p>A 75-year-old woman presented at a previous general hospital with anterior chest swelling. She was diagnosed with metastasis from follicular thyroid carcinoma by needle biopsy and referred to our hospital. CT scan revealed an 18 cm×11 cm massive tumor in the anterior mediastinum which involved invasion of the sternum, ribs and clavicles. Also, a 1 cm diameter thyroid tumor and multiple lymph node metastases were revealed. PET scan revealed metastases of the bilateral humeri and left ilium. We diagnosed T1N1bM1 stage IVC follicular thyroid carcinoma. Because there was no invasion into the large vessels, we performed an operation and considered I131 therapy as an adjuvant therapy. The anterior chest tumor could be resected with the sternum, ribs, and clavicles, and total thyroidectomy, neck dissection, and dissection of the mediastinal lymph nodes were also performed. The chest wall was reconstructed by polypropylene mesh. Histological examination of the massive chest wall tumor yielded a diagnosis of mediastinal lymph node metastasis of follicular thyroid carcinoma involving the chest wall. I131 therapy could not be performed due to left optic nerve metastasis. Unfortunately, molecular target therapy also could not be continued more than 3 months due to an adverse event. Nevertheless the patient has survived for 31 months after the operation and her daily life has not been adversely affected. Surgical resection is a potentially viable treatment option for chest wall metastasis of differentiated thyroid cancer.</p>

Journal

References(4)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top