A Case of Sarcoidosis, Complaining of Nasal Obstruction due to Nasal Mucosal Lesion

  • Uetake Takeshi
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Takahashi Naoki
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Suzuki Toshio
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Kudoh Shoji
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Hirayama Masakiyo
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Kimura Hitoshi
    Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
  • Miyashita Hisao
    Department of Otolaryngology, Tokyo Metropolitan Komagome Hospital
  • Motizuki Takanori
    Department of Pathology, Tokyo Metropolitan Komagome Hospital
  • Hongo Osamu
    Department of Dermatology, Tokyo Metropolitan Komagome Hospital
  • Kaneda Hideki
    Department of Internal Medicine, Shirai Chuo Hospital

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Other Title
  • 鼻粘膜病変による高度の鼻閉を初発としたサルコイドーシスの1例  41報告例の文献的考察
  • 41報告例の文献的考察

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Abstract

A 28-year-old man was admitted with nasal stuffiness of 12 months' duration. physical examination revealed generalized discrete enlargement of the lymphnodes and multiple subcutaneous nodules. He had a severe nasal obstruction, due to marked granulomatous hypertrophy of the nasal septum and bilateral inferior turbinates. The chest X-ray film showed BHL and diffuse small nodular lesions in both lung fields. There was abnormal 67Ga accumulation in the nose as well as in the lung. A diagnosis of sarcoidosis was confirmed by biopsy of nasal mucosa, lymphnode, subcutaneous nodule and by transbronchial lung biopsy, which showed non-caseating granuloma. The nasal mucosal lesion as well as intra- and extra-thoracic lesions responded to corticosteroid therapy with marked improvement.

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