高血圧・冠動脈狭窄と心筋虚血性病変

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  • Effect of Blood Pressure and Coronary Stenosis on Myocardial Ischemic Lesions
  • コウケツアツ カンドウミャク キョウサク ト シンキンキョケツセイ ビョウヘン ロウネンシャ レンゾクボウケンレイ ニ ツイテ ノ ケントウ
  • 老年者連続剖検例についての検討

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Pathological examinations of the heart and the coronary arteries were performed in 418 consecutive autopsy cases.<br>There was a close correlation of large ischemic myocardial lesions to coronary stenosis. Myocardial infarctions or large myocardial scarrings were almost always observed in the presence of complete occlusion in any one of the main coronary arteries, while large myocardial lesions were frequently observed in those with significant reduction of the luminal area of the main coronary arteries, especially when at least 2 main branches of the arteries were severely stenosed.<br>Although large myocardial lesions were more frequent in the cases with severe hypertension than in those with normal blood pressure or moderate hypertension, there was no significant differences in the incidence of large myocardial lesions within the groups with the same severity of coronary stenosis regardless of blood pressure. Therefore, the high incidence of large myocardial lesions in the cases with severe hypertension was considered to be a secondary result basing on the high incidence of severe coronary stenosis in those cases.

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