血球貪食症候群を伴ったB細胞性びまん性大細胞型悪性リンパ腫

DOI Web Site PubMed 被引用文献3件 参考文献9件

書誌事項

タイトル別名
  • Diffuse B-cell Lymphoma Associated with Hemophagocytic Syndrome
  • ケッキュウ ドンショク ショウコウグン オ トモナッタ Bサイボウセイ ビマン

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説明

An 84-year-old female was admitted to our hospital because of fever. Physical examination and computed tomography revealed hepatosplenomegaly without lymphadenopathy. Anemia and thrombocytopenia were noted and the serum levels of LDH, IL-6 and sIL-2R were elevated. Bone marrow aspiration showed infiltration of lymphoma cells and proliferation of histiocytes with hemophagocytosis. Southern blot analyses revealed rearrangements of both IgJH and IgJK genes. She received corticosteroids with improvement of her general state but she died on the 110th hospital day. Necropsy of the spleen showed diffusely proliferating large lymphoma cells, immunoreactive for B cell marker L-26, and scattered histiocytes with hemophagocytosis.

収録刊行物

  • 臨床血液

    臨床血液 37 (2), 161-164, 1996

    一般社団法人 日本血液学会

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