Ｓｉｍｐｌａｔｅ　ＩＩを用いた出血時間の測定

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タイトル別名
  • Clinical Trial of New Bleeding Time Device (Simplate II)
  • Simplate 2を用いた出血時間の測定
  • Simplate 2 オ モチイタ シュッケツ ジカン ノ ソクテイ

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A clinical trial was made for Simplate II comparing with the Template and the Duke methods.<br>The mean bleeding times were 4.36 minutes (S. D.=1.33, n=30, healthy volunteers) with Simplate II, 6.35 minutes (S. D.=1.99, n=14) with the Template method, and 2.92 minutes (S. D.=0.90, n=14) with the Duke method. Those with both Simplate II and the Template methods revealed a good correlation (R=0.665, P<0.01), however, those with Simplate II and the Duke method showed a poor correlation (R=0.479, P<0.05).<br>Bleeding times before and after aspirin ingestion (dosis ranging from 7 mg/kg/day to 50 mg/kg/day, 3 times daily, for 3 days) were measured by these 3 methods in 4 adults and found that those after aspirin ingestion, irrespective of low or high doses, were significantly prolonged in both Simplate II and the Template method, but not so much prolonged with the Duke method.<br>In 6 patients with platelet dysfunction (Bernard-Soulier syndrome, thrombasthenia, von Willebrand disease), prominent prolongation of bleeding times was observed in both Simplate II and the Duke method.<br>Simplate II is a sufficiently reliable device of bleeding time, and simple to use. However, it sometimes leaves a scar on the forearm. Therefore, we should carefully consider the clinical application of this device.

収録刊行物

  • 臨床血液

    臨床血液 23 (2), 144-149, 1982

    一般社団法人 日本血液学会

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