血液疾患患者の間質性肺炎における血清中ｓｏｌｕｂｌｅ　ｉｎｔｅｒｌｅｕｋｉｎ‐２　ｒｅｃｅｐｔｏｒ測定の診断的意義

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タイトル別名
  • Diagnostic Value of Serum Soluble Interleukin-2 Receptor Levels in Interstitial Pneumonia of the Patients with Hematological Disorders.
  • 血液疾患患者の間質性肺炎における血清中soluble interleukin-2 receptor測定の診断的意義
  • ケツエキ シッカン カンジャ ノ カンシツセイ ハイエン ニ オケル ケッセイ

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Serum levels of soluble interleukin-2 receptor (SIL-2R) and C-reactive protein (CRP) were measured in 12 patients with interstitial pneumonia (IP) and 10 patients with bacterial pneumonia (BP) of hematological malignancies. Mean SIL-2R levels (U/ml) were 394±140 in normal controls, 755±320 in BP, and 2328±943 in IP. A significantly higher level was found in IP than BP (p<0.05). Moreover, the SIL-2R/CRP ratio which was over 260 in all cases of IP completely distingwished IP from BP. Levels of SIL-2R rose before the onset of IP and were closely associated with clinical course in most cases. From these results, measurement of serum SIL-2R may be useful for the diagnosis and monitoring of the clinical course of IP complicated with hematological diseases.

収録刊行物

  • 臨床血液

    臨床血液 38 (2), 146-148, 1997

    一般社団法人 日本血液学会

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