Antiplatelet Antibody and Circulating Immune Complexes in Patients with Idiopathic Thrombocytopenic Purpura

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  • 特発性血小板減少性紫斑病における血小板抗体および血中免疫複合体
  • トクハツセイ ケッショウバン ゲンショウセイ シハンビョウ ニ オケル ケッシ

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Description

Platelet antibodies (PLAB) and circulating immune complexes (CIC) were measured to investigate the role of PLAB and CIC in the mechanisms of thrombocytopenia in patients with idiopathic thrombocytopenic purpura (ITP). These patients had increased amounts of platelet-associated immunoglobulins (PAIG), platelet-binding immunoglobulins (PBIG) and CIC levels. The PBIG or CIC values were found to be no correlation with the platelet counts in contrast with the existence of inverse correlation between the PAIG values and the platelet counts. These results suggest that PBIG and CIC may not be so important factors as PAIG in the mechanisms of thrombocytopenia in patients with ITP.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 26 (2), 177-183, 1985

    The Japanese Society of Hematology

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